Type 2 Diabetes
Overview
Type 2 diabetes is a common condition that causes the level of sugar (glucose) in the blood to become too high. It can cause symptoms like excessive thirst, needing to pee a lot and tiredness. It can also increase your risk of getting serious problems with your eyes, heart and nerves. It's a lifelong condition that can affect your everyday life. You may need to change your diet, take medicines and have regular check-ups.
Causes
It's caused by problems with a chemical in the body (hormone) called insulin. It's often linked to being overweight or inactive, or having a family history of type 2 diabetes.
Research Summary
759
Diabetes II trials open globally
Global trials - phase
Phase indicates how far along the treatment is in the development process. Phase 1 indicates very early, phase 4 is later.
42
Diabetes II trials open in the UK
9,508
Participants required for UK studies
Global trials - interventions
Intervention is the type of treatment that will be being tested during the trial.
Nye Spotlight Trials
Evaluation of Diabetes and WELLbeing Programme
Study type: interventional
400 estimated participants
Recruitment ends 2023-03-31
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Medway Community Healthcare, Gillingham
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Blackthorn Trust, Maidstone
About the study
This study evaluates the impact of 'DWELL' - a 12-week psycho-social education programme designed to help people with type 2 diabetes to better self-manage...
Eligibility
Inclusion Criteria:
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Clinical diagnosis of type 2 diabetes
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Over the age of 18
Exclusion Criteria:
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Under the age of 18...
Prevalence and Determinants of Subclinical Cardiovascular Dysfunction in Adults With Type 2 Diabetes Mellitus
Study type: Observational
200 estimated participants
Recruitment ends 2022-06-01
University of Leicester, Leicester
About the study
Background: Heart failure is a major cause of morbidity and mortality in diabetes mellitus, but its pathophysiology is poorly understood.
Aim: To determine the prevalence and determinants...
Eligibility
Inclusion Criteria:
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Participant is willing and able to give informed consent for participation in the study.
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Male or Female, aged ≥18 and ≤75 years.
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Diagnosed with Stable type 2 diabetes (determined...
Longitudinal Assessment of Multiple Organs in Patients With Type 2 Diabetes
Study type: Observational
150 estimated participants
Recruitment ends 2026-09-30
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Aintree University Hospital NHS Foundation Trust, Liverpool
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Oxford University Hospitals NHS Foundation Trust, Oxford
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Royal Free Hospital NHS Foundation Trust, London
About the study
MODIFY study is a multi-centre prospective, longitudinal, observational cohort study which aims to recruit 150 adult patients with type 2 diabetes recruited...
Eligibility
Inclusion Criteria:
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Male or female over 18 years of age and diagnosed with type 2 diabetes.
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Participant currently taking glucose lowering therapy.
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Participant willing and able to give informed...
Assessment of the Impact of a Personalised Nutrition Intervention in Impaired Glucose Regulation
Study type: interventional
180 estimated participants
Recruitment ends 2022-08-01
Imperial Clinical Research Facility, London
About the study
This study will determine if DNA-based dietary guidelines can improve glucose regulation in pre-diabetic individuals significantly more than standard dietary...
Eligibility
Inclusion Criteria:
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Provision of signed and dated informed consent form
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Adults over 18 years of age
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Impaired glucose regulation including impaired...